It’s 2025 and the “longevity” buzzword is everywhere. If you’re a NewBeauty subscriber, you’ve read about NAD+ and the benefits it has, not only for our skin, but also our overall health. From skin care to supplements, the next-gen ingredient (nicotinamide adenine dinucleotide) is a molecule found inside the mitochondria of all living cells, and it generates the ATP (energy) our cells need to function at their best.
One of the brands paving the way in the NAD sector is Aramore, a skin-care brand developed by Harvard scientists. In fact, the brand’s cofounder, Anna Mandinova, is a top skin biologist from the university and discovered how to boost NAD+ in skin cells, which had never been done before. By itself, the NAD+ molecule is too large to penetrate the skin effectively, but you can boost the NAD+. Mandinova and her team developed a proprietary combination of NAD+ precursors (cellular nutrients) and synergistic compounds that are easily absorbed. This mix of ingredients (NAD+ Complex) are delivered “in a coordinated way” to rejuvenate the skin.
According to Mandinova and her team of esteemed experts, if you are older than 20, your NAD+ levels have already begun to decline, which means your cells “have an ever-decreasing supply of energy. In the skin specifically, stem cells become underpowered, so they make fewer new skin cells.” This leads to signs of aging like loss of firmness and elasticity, lines and wrinkles, and more. By boosting NAD+ levels, it “jumpstarts stem cells to make fresh, new skin cells at a healthy rate, essentially delaying the aging process.” Here, we learn more about Aramore’s best-selling serum, the NAD+ Cell Energizing Treatment ($92).
The Benefits of This NAD+ Serum
Let’s start with the key ingredient, the NAD+ Complex. Mandinova’s research showed that “boosting NAD+ with NMN combined with ketones and fatty acids normalizes skin stem cell differentiation into skin cells.” For those of us who didn’t excel in science, this means that the formula can provide the healthy replacement of skin cells that we begin to lose with age. However, it’s important to understand that this serum isn’t physically altering the biology of the skin; it’s helping it function optimally. The addition of antioxidants provides protection against free-radical damage, and sodium hyaluronate (a more effective type of hyaluronic acid) keeps skin hydrated.
In a four-week clinical study on 29 panelists, 100 percent of them showed improvement in 12 key metrics of skin health and longevity: evenness of skin tone, age spots, fine lines, firmness, radiance and glow, brightness, plumpness, smoothness, softness, suppleness, moisturization and skin barrier strength. The serum also strengthened the skin barrier by 53 percent after eight weeks of use. What I noticed on my mid-30s skin was a much smoother texture and a firmer feel, particularly in my lower face. The brand says you should see a change in the quality of your skin after four weeks because the serum is “engineered to work with your skin’s natural 28-day regenerative cycle.”
How to Use This Serum
In the morning and evening, apply two or three pumps on clean skin. The brand says this treatment should replace your serum step, but you can also layer it over lightweight serums. I didn’t need an additional hyaluronic acid serum or hydrating serum because it contains humectants. However, if your skin feels like it needs more moisture, you could add an additional serum or layer a moisturizer on top. If it were winter, I would layer a cream on top. And of course, sunscreen always. Because it contains antioxidants, it pairs really nicely with SPF. I love the silky texture of the lotiony serum and how quickly it absorbs. It feels great and doesn’t pill when layered with other products.
