For women over 50, skin-care needs change, but expectations don’t. That’s why so many in this age group are turning to SkinMedica TNS Advanced+ Serum ($295), a growth factor–powered formula designed to target visible signs of aging. In a recent survey of more than 1,300 NewBeauty readers,* women in their 50s, 60s and 70s repeatedly named this as their go-to for smoother, firmer, more radiant skin.
A Multitasker for Aging Skin
For women dealing with multiple concerns like fine lines, loss of firmness and uneven tone, many said the serum delivers on all fronts. One 59-year-old with aging skin and hyperpigmentation said the product has “definitely helped the sagging texture of my skin,” crediting its peptides and growth factors for improvements in both fine lines and discoloration. Another 63-year-old added that it “leaves skin feeling toned,” while others reported visibly smoother, more youthful-looking skin in just a few weeks.
Post-Procedure Powerhouse
Several readers shared that they rely on TNS Advanced+ after in-office treatments to boost results and support recovery. One 56-year-old said, “Love this product. It makes my skin feel and look youthful. Very effective after treatments like microneedling.” Another, 61, described it as “a game changer” that helped her maintain the results of a cosmetic procedure longer.
Results That Justify the Price
Nearly every respondent acknowledged that the serum is an investment. But for many, the results speak for themselves. A 58-year-old shared that although the product is “pricey,” it’s “amazing” and has “really helped with texture and hydration.” Another reader, 63, called it “one of the best products I’ve used,” adding that while it’s highly expensive, it’s also “effective—especially compared to other high-priced products.”
A Decade of Loyalty
Some women have stayed loyal to the product for years, and have the compliments to prove it. A 66-year-old said she’s used the serum since a Fraxel treatment over a decade ago, and it has “transformed [her] face.” She added, “Although I’m 66, I am often mistaken for much younger and I do believe it is because of this product.” She even recalled a recent moment when a stranger complimented her glow at a restaurant, prompting her friend (also a TNS user) to reveal the secret: SkinMedica.
Perhaps the strongest endorsement came from a 70-year-old who used the serum throughout her 60s. “I used SkinMedica’s TNS Essential Serum for probably three to four years during my 60s,” she said. “I can honestly say that during that time my skin improved significantly and I did not appear to age while using it.”
And when it comes to real anti-aging results, that might just be the ultimate proof.
*Source: BeautyEngine Advanced Research, 2025
